Aluminum

Physiological function
Dietary sources
Toxicity of A1

I.  Physiological function

1. Several biological functions for A1 have been suggested from indirect evidence but A1 has not been proven essential for animals.

II.  Dietary sources

1. A1 cooking utensils and beverage cans
2. Ingested soil
3. Plants grown in wet, low-oxygen soil take up increased amounts of Al

III.  Toxicity of A1

1. Chronic A1 excess results in secondary P deficiency
   1. Reduced P absorption and reduced serum P
   2. Lower bone ash content
   3. Disturbances in carbohydrate and P metabolism (reduced ATP: ADP ratio)
   4. Reduced working capacity
2. High A1 content of forage may contribute to hypomagnesemic tetany
3. Involved in Alzheimer disease?

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