Ultra Trace Elements

I.  Criteria for essentiality of trace elements

1. Chemically suitable for biological functions
2. Low molecular weight
3. Proper atomic structure
4. Transition element
5. Must form chelates
6. Act as a catalyst
7. Ubiquitous in earth's crust and sea water
8. Present in plants and animals
9. Relatively low toxicity
10. Homeostatic mechanisms implied
    Controlled serum levels
    Rapid excretion rates
    Lack of excessive accumulation
11. Its deficiency must reproductively result in an impairment of a function, or functions, from optimal to suboptimal

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